The National University of Rosario was created in 1968 through Law 17,987. Its founding structure was a detachment of the Universidad Nacional del Litoral from which it took its first academic and administrative bodies, which at that time consisted of: the faculties of Medical Sciences, Sciences, Engineering and Architecture, Economic Sciences, Philosophy, Law and Political Sciences, Dentistry, Agrarian Sciences and the Hospital-schools and secondary schools that depended on it, in addition to the Higher Institute of Music of Rosario.
Since its inception, the National University of Rosario began an active relationship with Rosario society from which it generated each of the projects that it launched and that was expressed in sustained growth according to the demands of the region.
Its current structure consists of 12 faculties, 3 secondary schools, and 1 center for interdisciplinary studies. It has a building area of 68,000 square meters where an academic offer is made up of 171 postgraduate degrees, 63 undergraduate degrees, 15 technical courses, 53 intermediate degrees, 26 degrees by articulation with the non-university higher education system, and 32 postgraduate degrees.
In recent years, the virtual campus was added to this academic offer, from which courses are offered in the distance mode and using Web support as a teaching environment.