The Master in Life Sciences program - RNA and Enzymes Sciences (RNAES) is a training course characterized by a strong recognized and specific expertise in the field of molecular and cellular biology of RNAs and Enzymology.
RNAES relies heavily on the teaching team made up of members of the ARN-RNP and Molecular and Structural Enzymology teams of the UMR IMoPA UL-CNRS 7365, which is internationally renowned, but also on external speakers, from French universities or Foreign. Second-year Master's courses are taught in English only.
Objectives and expected competencies
Graduates will be able to develop experimental plans and strategies to produce and characterize RNA molecules or enzymes, to conduct projects aimed at studying the activity, structure, cellular functions, of these macromolecules. This knowledge and know-how will enable graduates either to enter the workforce at Bac +5 or to pursue a Ph.D. Students will have to choose between two options:
Option RNA Science (RNAS)
It aims to train specialists able to intervene on fundamental biological problems involving RNA, interpretation of transcriptomic data, but also in the development of therapeutic approaches using RNA molecules
Option Enzyme Science (ES)
It aims to train molecular enzymology specialists able to decipher fundamental molecular processes involving enzymes. An integrated view of the structure of enzymes, their dynamics, and their function is also needed for the design of more efficient catalysts used in industrial biotechnology for the production of chemicals or new drugs.
Training for research
Training for and for research starts in the first year of the Master. The S7 semester aims at acquiring a BBRMC disciplinary base (description of concepts and evolution of knowledge, derived from research data).
In S8, students are sensitized and gradually trained to research through studies of scientific publications, in different ways (journal club, problem-based learning, etc.), completed during semester 8 by learning oral and written communication in English in the EU framework of scientific English.
Practical work during the S7-S9 semesters is used to establish a good laboratory and regulatory practices or to apply theoretical concepts applied to macromolecules, cells, tissues, and the whole organism and to carry out an integrated experimental work. from experience design, implementation, data analysis or field situation analysis.
This practical introduction, in particular in S7 and S8, facilitates their handling of the subject of internship of a minimum duration of 8 weeks at the end of semester S8. This period of introduction to basic or applied research may be extended during the summer period (internship up to 16 weeks).
During semester S10, students will be trained in research and will contribute significantly to a fundamental research project or application. The choice of the end-of-study internship subject depends on the professional project of each candidate; it is either towards a direct insertion or towards the doctoral pursuit or a reorientation; the choice of internship in France or outside France; the training modality (initial training or alternation training) Finally, the internship in a company is also guided by a possible hiring at the end of this period.
The course is mainly intended for research and thus the continuation of the course by the preparation of a Ph.D. in the fields of molecular and cellular biology, biochemistry, enzymology or structural biology.
In this sense, the second semester of the training is entirely dedicated to a research internship in international recognition teams in the fields of RNA or enzyme studies, in Nancy, France or abroad.