This course enables you to study cutting-edge molecular methods employed for the understanding of molecular mechanisms of diseases and for their diagnosis and treatment. Your studies will be underpinned by essential knowledge in genetics, cell signalling and molecular medicine.
You will be offered the flexibility to select option modules that reflect your own interest in molecular biology and these will be combined with core modules and an independent research project. The course is suitable for newly qualified graduates, those employed in related work and those with medical qualifications.
The following modules are indicative of what you will study on this course.
Molecular and Cellular Therapeutics
This module reviews and discusses the ways in which molecular biology has been used to treat inherited and acquired diseases. You will investigate the ethics and legislation involved in the use of novel therapies in humans.
Molecular Science and Diagnostics
This module is designed to make you aware of the impact of molecular biology on the diagnosis of human diseases. You will critically review the technologies and determine the advantages and disadvantages associated with each diagnostic strategy. Issues of accuracy, implementation, ethics and safety will be addressed.
Principles of Molecular Medicine
The module provides you with a critical appreciation of the human genome, its regulation, the functional significance of gene mutations and current approaches to identification of human genetic disorders. Topics covered include molecular basis of host-pathogen interaction; molecular pathology of disease with simple genetics; molecular genetics of disease; complex systems, immunogenetics and disease; and molecular genetics of cancer.
Postgraduate Research Methods
You will be able to develop your skills in information retrieval, critical analysis and presentation relevant to your research topic, and form a clear plan for your project.
This module aims to enhance your skills of self-management, experimental design, critical analysis and interpretation of data, enabling you to present and justify your research.
Cell Signalling and Genetics
This module provides up-to-date information on cell signalling processes coupling surface receptor engagement to changes in gene expression. Transcriptional, post-transcriptional and post-translational mechanisms are discussed in relation to selected cell-signalling pathways responsible for controlling cell functions such as cell cycle, cell differentiation and cell death. Examples of defective cell signalling through inherited and somatically acquired mutations in signalling components will be highlighted in relation to human disease.
Extended Postgraduate Project
This module gives you the opportunity to investigate an appropriate research topic, generate and critically analyse data, and present your results and discuss findings in the context of previously published work. The project proposed and undertaken must include rigorous and critical analysis of data with a high level of initiative. This module is intended for students wishing to gain greater research experience and includes an extended period of research activity and extended assessment regime.
You will analyse and discuss cellular and molecular aspects of innate and adaptive immune responses, and advances in modern methods for disease diagnosis and treatment. This will include strategies available for the diagnosis of inherited and acquired immunological disorders, normal and pathological immune responses to extracellular and intracellular pathogens, transplantation of organs and tissues, immune surveillance of tumours, autoimmune and immunodeficiency disorders.
The module aims to investigate the role of immunological tools such as vaccines, monoclonal antibodies and cytokines in the treatment of human disease.
Bioinformatics is an exciting new discipline at the interface of computer science, information and biology and is playing a crucial role in the development of personalised medicine. From genome sequencing projects thigh to rational drug design protein engineering it offers great opportunities for enhancing our understanding of biology at the molecular level and for the developments of new therapeutics. Topics covered include analysis of protein sequences and structure, modelling protein structure and function, rational drug design, protein structure predication and protein engineering.
This module will introduce the theoretical and practical underpinnings of systems biology. The emphasis is on studies of entire systems, assisted by the use of bioinformatics and how the knowledge from these may be applied to medicine. The module will examine databases and other resources as well as discuss issues key to the studies of entire systems.
You will develop a range of course-specific and transferable skills that will enhance your employment prospects, career progression and research opportunities in the UK and/ or overseas. It is anticipated that a significant number of graduates will go on to pursue a career in research after registering for a higher degree. Others will seek employment in healthcare laboratories, industry, research laboratories, government laboratories or academia in the UK or worldwide. One of the strengths of this degree is the mixture of backgrounds/ experience and career aspirations of the students recruited.
The course is accredited by the Institute of Biomedical Science (IBMS).
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